With Ellen DeGeneres’ chat show ending after 19 seasons, many fans have reflected on her career’s highs and lows. In a more recent case, the 64-year-old claimed “excruciating” back pain after contracting COVID-19 at the height of the pandemic.

DeGeneres decided to step away from the spotlight amid charges that her show was a toxic workplace, instead seeking to spend more time fulfilling her passion for animal conservation, Other early warning signs of Covid included fever or chills, cough, shortness of breath, tiredness, headache, the new loss of taste or smell, sore throat, congestion or runny nose, nausea or vomiting, and diarrhea.